Abstract
Catheter-associated urinary tract infection is among the most common types of infections in the United States. One of the potential solutions is to modify the catheter surface with antimicrobial agents to prevent bacterial attachment and biofilm formation. In this study, silver nanoparticles were covalently-bonded on polyvinylchloride (PVC) film, and zinc oxide nanowires with a radiating acicular structure were then self-assembled on the composite surface. The composite film reduced the attachment of Staphylococcus aureus by nearly two orders of magnitude in 24 h. The integration of silver nanoparticles and zinc oxide nanowires holds potential for antimicrobial applications.
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