Abstract

Polypoidal choroidal vasculopathy (PCV) is an age-related macular degeneration (AMD) subtype and is seen particularly in Asians. There is a disparity in response to intravitreal anti-vascular endothelial growth factor (VEGF) treatments between PCV and typical AMD, and the preferred treatment for PCV has remained unclear. Recent researches suggest that PCV belongs to a condition characterized by pachychoroid and disturbance in the choroidal circulation seems to be central to its pathogenesis. In this review, we summarize the clinical and imaging features, diagnostic criteria, and current management guidelines of PCV.

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