Polymorphous Low-Grade Adenocarcinoma: A Rare Cause of Long-term Epistaxis

Abstract

Polymorphous low-grade adenocarcinoma (PLGA) of the paranasal sinus is an extremely rare disease. PLGA is a minor salivary gland neoplasm that occurs mostly in the junction of the soft and hard palate, followed by the buccal mucosa and upper lip. Only a few cases have been reported in the sinonasal area. PLGA generally follows a benign clinical course with frequent perineural invasion but low metastatic potential.