Abstract
Persistent Pulmonary Hypertension of the Newborn (PPHN) is characterized by elevated pulmonary vascular resistance with extrapulmonary right to left shunting causing life threatening hypoxemia. Endogenous Nitric Oxide is critical for regulation of pulmonary vascular resistance and the transition of pulmonary circulation at birth. Endothelial cells generate Nitric Oxide from the precursor L …
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