Abstract
Various mutations in the BMP15 and GDF9 genes belonging to the transforming growth factor-β (TGF-β) superfamily have been shown to affect the prolificacy in sheep. Increasing the litter size is critical to the profitability of sheep production, but focusing on increasing the number of lambs born is only one of many factors that make sheep farming profitable. The study aimed to identify polymorphisms in BMP15 and GDF9 in Romanov, Wrzosówka, and Podhale Zackiel sheep breeds. The polymorphism of the coding parts of the BMP15 and GDF9 genes was determined based on DNA sequence analysis. Statistical analysis showed a significant relationship (p≤0.05) between the identified leucine deletion at the BMP15 locus (c.28_30delCTT) and increased fertility in heterozygous sheep. Statistically significant differences in the level of fertility were also identified between individuals with a mutation in the GDF9 gene - (c.978A> G, G6 - c.994G> A) and carriers of mutations in two BMP15 genes and GDF9 simultaneously.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
