Abstract
Abstract In the past few years, we have witnessed tremendous research progress in under fabrication of biosensor technology based on polymeric micelles. Nowadays, advances of polymeric micelles in drug delivery have been recently increased the number of publications; however, the application for the sensor technology development still limited. Polymers in the form of micelles are attractive and promising candidates for fabrication of sensors applications because of their functional properties, in particular high surface-to-volume ratio aspect. Macromolecular self-assembly has provided a good means which to selectively assemble polymers into well-defined nanostructures such as polymeric micelles, vesicles, and other morphologies. Polymeric micelles-based nanocomposites are based designed platform for fabrication of biosensor. Polymeric micelles that respond to external stimuli (such as temperature, pH, magnetic field, and redox) to afford a change in morphology, structure, and controlled performance of fabricated biosensor are also introduced. The objective of this chapter is to describe the current perspectives regarding to progress and limitations for polymeric micelles-based biosensor technology. These novel devises could be used for quantification of high risk toxicants in the human body. This technology includes the production of biochips to detect proteins, DNA neurotransmitters, and small molecule, such as glucose.
Published Version
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