Abstract
In this research, we developed strontium-substituted apatite (Sr-HAP) scaffolds using the polymeric sponge replication method. Tissue engineering is a potential new technology for replacing damaged tissue with biocompatible artificial templates. The scaffolds prepared with an interconnected porous microstructure with pore sizes ranging from 400 to 622 μm were created as engineering constructions. The physicochemical properties of the Sr-HAP scaffolds were characterized by various techniques such as X-ray diffraction (XRD), Field emission scanning electron microscopy (FE-SEM), and Energy dispersion spectroscopy (EDS). Immersion tests in simulated body fluid (SBF) solution was used to assess the surface reactivity of the resulting scaffolds. More critically, MTT assay tests were utilized to investigate the cell viability of porous Sr-HAP scaffold at varying doses of 10–1000 μg/mL for 24 h. The porosity Sr-HAP scaffolds developed in this study are a potential tissue engineering candidate.
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