Abstract
Copper(II), cobalt(II), nickel(II), manganese(II) and cadmium(II) polymer complexes of N,N`-1,4-phenylene (2-hyboxynaphthaliden imine) have been synthesized. The structure of Schiff base and polymer complexes have been characterized by elemental analysis, spectral (FT-IR, UV–Vis, 1H NMR and ESR), X-ray diffraction, magnetic moment measurements and molar conductance. The molar conductivity data indicates that the chelates are non-electrolytes for polymer complexes (1, 4 & 5). The analytical data support 1:1 (M:L) stoichiometry. FT-IR data shows the ligand function as bis-bidentate coordination through ONNO donor system. The electronic spectra along with magnetic data suggest octahedral geometry for polymer complexes. The XRD patterns of the ligand and its polymer complexes showed the polycrystalline natures. The ligand and its complexes were studied for their microbial activity against some bacteria and fungi. Our results indicated that ligand and polymer complex (3) have higher effect against S. aureus than that of penicillin by at least nine times; this effect increased by increasing the concentration. Molecular docking was used to predict the binding between ligand and two receptors of the crystal structure of Staphylococcus aureus (3q8u) and the crystal structure of E. coli (3t88). It was found that, the receptor of Staphylococcus aureu (3q8u) shows the best interaction than the receptor of E. coli (3t88) with the ligand.
Published Version
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