Polymer based whispering gallery mode laser for biosensing applications

Abstract

Whispering gallery mode lasers are of interest for a wide range of applications and especially biological sensing, exploiting the dependence of the resonance wavelengths on the surrounding refractive index. Upon lasing, the Q factors of the resonances are greatly improved, enabling measurements of wavelength shifts with increased accuracy. A way forward to improve the performance of the refractive index sensing mechanism is to reduce the size of the optical resonator, as the refractive index sensitivity is inversely proportional to the resonator dimensions. However, as the lasing threshold is believed to depend on the Q factor among other parameters, and the reduction of the microresonator size results in lower Q, this poses additional challenges for reaching the lasing threshold. In this letter, we demonstrate lasing in 10 μm diameter dye doped polystyrene microspheres in aqueous solution, the smallest polystyrene microsphere lasers ever reported in these conditions. We also investigate the dependence of the lasing threshold on the Q factor by changing the refractive index surrounding the sphere, highlighting a much stronger dependency than initially reported.