Abstract
Hyaluronate and alginate are non-toxic and biocompatible polymers, which can be used for surface modification and functionalization of many kinds of materials. Electrophoretic deposition (EPD) has several advantages, including its versatility, simplicity, and ability to coat substrates with complex shapes, and is used for the creation of antimicrobial or hydrophobic coatings on metallic biomaterials, among other applications. However, its utilization for applying biopolymer layers on textiles is very limited due to the more complex structure and spatial characteristics of fibrous materials. The aim of this research was to analyze the effects of selected EPD process parameters and the structural characteristics of fibrous carriers on the kinetics of the process and the microscopic characteristics of the deposited layers. The influence of solution characteristics, process parameters, and carrier structures obtained using two different techniques (melt blown and spun-bonded) were analyzed. The morphology and structure of the created deposits were analyzed using scanning electron microscopy and computed tomography, and molecular structure analysis was performed with Fourier Transform Infrared spectroscopy. The surface mass and thickness of fibrous poly (lactic acid)-based carriers were analyzed in accordance with the respective standards. This study serves as a basis for discussion and further development of this method with regard to fibrous materials for medical applications.
Highlights
Sodium hyaluronate (SH) and sodium alginate (SA) are non-toxic, biocompatible, and biodegradable polymers, which can be used for surface modification and functionalization of many kinds of materials [1]
The results confirm that the higher concentration of polymer solutions, which is associated with higher conductivity and surface tension, resulted in higher deposit mass
Differences in the zeta potential of the polymers did not result in differences in the electrophoretic deposition process between sodium alginate and sodium hyaluronate or between sodium hyaluronate of two different molecular weights
Summary
Sodium hyaluronate (SH) and sodium alginate (SA) are non-toxic, biocompatible, and biodegradable polymers, which can be used for surface modification and functionalization of many kinds of materials [1]. Its ability to absorb and retain large amounts of water is a characteristic feature, and in tissue engineering, it affects the migration, adhesion, and proliferation of cells [3,4,5]. It exhibits characteristic viscoelastic properties [6], which are used in the production of films, fibers, and porous structures, as well as organic/inorganic composites for biomedical applications [7,8]. Nontoxicity, and biocompatibility, it is used in tissue engineering and biomedicine [13,14,15] for the fabrication of scaffolds, wound dressings, and fibers
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