Abstract
The 3,3′,5,5′-tetramethylenebiphenyl tetraanion, prepared in good yield by metallation-elimination, gives tetrasubstituted biphenyl derivatives, e.g., with H 2O, D 2O, methyl iodide, and trimethylsilyl chloride. The reaction sequence, starting from alkylated cyclohexanones, provides a general synthetic route to symmetrical polysubstituted biphenyls.
Published Version
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