Abstract
Several synthetic routes to mono- and dihydroxynaphthazarins bearing an acetyl side-chain have been explored. Methoxynaphthazarin 1 has always been the starting material. Acylation is brought about via a photo-Fries rearrangement of various adequately substituted acetoxynaphthalenes prepared in several steps from 1. Further steps including oxidative demethylation, hydrolysis and ether cleavage reactions, led to the desired mono- and dihydroxysubstituted acetylnaphthazarins. A new synthesis of Spinochrome A 24, a natural occurring pigment representative of this kind of naphthazarin derivatives, is described.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call