Abstract

Atomically precise nanoclusters comprising 1-100 atoms have emerged as a new class of nanomaterials with intriguing size-dependent physicochemical properties. The significant changes in the properties of nanoclusters were observed in tailoring the number of metal atoms and ligands that determines their functions and applicability. Since 1990, thiolated gold nanoclusters have been studied. The separation of monodispersed clusters was crucial and time-consuming. To address these shortcomings, several separation techniques have made it possibleto separate the series of metalnanoclusters with a precise composition of metals and ligands. Among these techniques, polyacrylamide gel electrophoresiswas utilized for hydrophilic cluster separation. This review shall focus on the principle, operation and application of thepolyacrylamide gel electrophoresistechnique to encourage a greater understanding of the characteristics and usefulness of this method.

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