Abstract
BackgroundTraditional medicine being ethnic is preferred worldwide even in these modern days. Obesity is a lifestyle disorder. Many chemically synthesized medicines are available. Poly-herbal medicines can be one of the safest alternatives with less side effects in treating obese patients.ResultsThe in vitro anti-lipase activity was carried out for a different concentration. The formulation of the poly-herbal tablets was designed using the Design Expert software. The pre-compression and post-compression studies show that the formulation F6 showed better results of all the formulations designed. Stability study results showed that the poly-herbal tablets were stable throughout the studies.ConclusionThe results show that F6 is the better formulation based on the tablet evaluation, and all the extracts showed inhibitory activity against pancreatic lipase indicating its active role in the treatment of obesity.
Highlights
Traditional medicine being ethnic is preferred worldwide even in these modern days
Surface responses of Design of Experiments (DoE) Surface responses of DoE are shown in Table 8 and Figs. 3, 4, and 5
The best results are obtained by the formulation F6 and is considered as the optimized one
Summary
Traditional medicine being ethnic is preferred worldwide even in these modern days. Poly-herbal medicines can be one of the safest alternatives with less side effects in treating obese patients. Obesity is a severe as well as chronic disorder which is an important risk factor for lifestyle-related chronic disease. The fats when consumed in excess get stored in the adipose tissue of the body. This accumulation leads further to other chronic diseases and disorders in human beings and acts as the risk factor. Obesity is said to be one of the considerable contributors of noncommunicable chronic disease worldwide
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