Abstract

The article presents the results of a study conducted to determine some validation indicators for the quanti-tative determination of HPLC of triamcinolone in “Polcortolone” tablets, such as correctness, accuracy, linearity and compatibility of the system. The studied method is characterized by high efficiency, stability and specifici-ty. The limits of the accuracy of the method vary from 98.77% to 100.53%; standard deviation of accuracy 0.128%, reliability interval ±0.135; linear indicator 0.05-0.4 mg / ml with density interval R2 = 0.998, linear re-gression function y = 20770.91x-187.12; The number of theoretical levels in the system was 8305, and the rela-tive remainder of the peak was 1.13. The proposed method has such indicators as correctness, accuracy, linearity and system compatibility and allows you to control the quality of the drug "Polcortolone" at the stages of production and sale.

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