Abstract

Accurate identification of the shape and texture properties of cervical cell nuclei and cytoplasm in the pap smear test is crucial for the diagnosis of cervical cancer. Fast and high-precision polarization modulation in the Polarization Indirect Microscopic Imaging (PIMI) is achieved by utilizing a liquid crystal polarization rotator. Imaging results of cervical cells show that the PIMI method can resolve detailed fine structural features of a cervical cell which are invisible in conventional microscopy. It also demonstrated the ability of embossed three-dimensional visualization as that in differential interference contrast microscopy (DIC), but with finer structural features.

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