Abstract
Traumatic brain injury (TBI) is a leading cause of cognitive disabilities worldwide. Impaired attention and memory following TBI are in part due to cholinergic dysregulation. This study is designed to test the hypothesis that NS-1738, a novel α7 nicotinic acetylcholine (Ach) receptor (α7-NAChR) type-I positive allosteric modulator (PAM), normalizes cholinergic neurotransmission and improves higher-order attention after experimental TBI in rats.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call