Abstract
Real world data remains limited in comparing the left atrial appendage occlusion (LAAO) devices with Amulet and the new Watchman FLX. This study aims to report a comparison of short term outcomes of a high volume, single center experience with watchman FLX and Amulet device. Consecutive patients who underwent LAAO using Watchman FLX or Amulet devices from Feb 2020 to July 2022 were included in the study. Institutional NCDR LAAO Registry was used as well as retrospective chart review performed to compare short term outcomes between both the groups. Patients undergoing LAAO with Watchman 2.5 or epicardial approach with Lariat were excluded. A total of 326 patients underwent LAAO including 230 Watchman FLX and 96 with Amulet. There were no differences in all available baseline characteristics including mean age (76.3 ±8.3 years), women (46%), mean CHA2DS2-VASc score, and HAS-BLED score (Table). The procedural time (74 ± 32.5 vs. 66 ± 19.5 mins; P=0.02) and contrast volume (54 ± 27.4 vs. 39.9 ± 19.6 P =<0.01) were significantly higher for Amulet as compared to Watchman FLX. No difference in procedural outcomes (Acute success, adverse events and residual leak) noted in immediate post procedure period and at 45 day follow-up. In a single-center, real world experience, LAAO with Amulet was associated with higher procedure time and contrast utilization with no difference in short term procedural outcome.
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