Abstract

Background and aims Endothelial dysfunction (DE)-a state of the vascular endothelium, which is accompanied by vazotonic, remodelic, anti-inflammatory and anticoagulant functions. The range of these disorders, the severity of each, and chronology of occurrence, the dynamic progression vary depending on the nosology pathology. Methods The investigated group included of 36 children (age -13,98 ± 0,16) with diagnosed primary arterial hypertension assotiated with DE. The scientific study was conducted in the Transcarpathian region of Ukraine. Results There were a significant difference in the levels of HDL (1,2 ± 0,31 mmmol/l to 69 ± 0,01 mmol/l, p Conclusion These dates presented the risk of thrombogenesis, but non significant. The levels of IL-1 and IL -6 were in the range of control values, but have a tendency to decline, according to our data. This fact indicated about the decrease in production of interleukins of child’s organism in the mountains region.

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