Clinical Paraclinical Parameters of Primary Arterial Hypertension in Adolescents

Abstract

We investigated children with primary arterial hypertension (PAH) from the Transcarpathian region of Ukraine (68 children, middle age 14.68 ± 0.84 years). In patients with arterial hypertension which PAH debuted in adolescence and have changes in lipid profile are formed pathological process in two ways: first way presented increase in total cholesterol associated with lower high-density lipoprotein (HDL) cholesterol indicators, and other is an increase in triglycerides with decreased levels of HDL cholesterol, according to data of M.M. Korenev et al. (2010, 2011). These changes in lipid profile is prognostically unfavorable signs of atherosclerosis which developed in the patients (1st way), in others — development of the metabolic syndrome in the young age (14–15 years), which we observed in our research. Our data are also relevant tendency. In children with PAH increase triglyceride levels (1.96 ± 0.04 mmol/l) associated with significant decrease in HDL cholesterol fraction (1.20 ± 0.31 mmol/l) which predicts development of the metabolic syndrome in the young age.