Abstract
Problematic issues of etiologic diagnosis and treatment of community-acquired and nosocomial pneumonia are being studied actively. At the same time specific features of pneumonia in patients with severe immune defects, against blood cancer including are studied insufficiently. By the result of microbiological examinations of 149 patients with pneumonia on the background of blood cancer, who have undergone treatment in hematological center of CE “Dnipropetrovsk local multi-field clinical hospital №4” in 2010-2012, bacterial causative agents were determined in 59,7% of accidents, among which gram-negative microorganisms made up 69,7%, gram-positive – 30,3%. In 63% of accidents the associations of causative agents were determined: the combination of fungal flora made up 58, 4% bacterial associations – 25, 8%. Invasive methods of research have demonstrated a considerably bigger informativeness in determination of possible etiological diagnosis of pneumonia. In determination of causative agent in fluid of brochoalveolar lavage the part of positive results made up 77,4% against 30,3% in examination of sputum.
Highlights
By the result of microbiological examinations of 149 patients with pneumonia on the background of blood cancer, who have undergone treatment in hematological center of CE “Dnipropetrovsk local multi-field clinical hospital ʋ4” in 2010-2012, bacterial causative agents were determined in 59,7% of accidents, among which gram-negative microorganisms made up 69,7%, gram-positive – 30,3%
Pharm. – 2009. – Vol 66, N 12, Suppl. 4. – P. 8-14
Summary
Ʉɥɸɱɨɜɿ ɫɥɨɜɚ: ɩɧɟɜɦɨɧɿɹ, ɿɧɮɟɤɰɿɣɧɿ ɡɛɭɞɧɢɤɢ, ɨɧɤɨɥɨɝɿɱɧɿ ɡɚɯɜɨɪɸɜɚɧɧɹ ɤɪɨɜɿ Key words: pneumonia, bacterial agent, blood cancer. By the result of microbiological examinations of 149 patients with pneumonia on the background of blood cancer, who have undergone treatment in hematological center of CE “Dnipropetrovsk local multi-field clinical hospital ʋ4” in 2010-2012, bacterial causative agents were determined in 59,7% of accidents, among which gram-negative microorganisms made up 69,7%, gram-positive – 30,3%. Ɇɚ ɠɚɥɶ, ɜɫɿ ɭɹɜɥɟɧɧɹ ɳɨɞɨ ɨɫɨɛɥɢɜɨɫɬɟɣ ɟɬɿɨɥɨɝɿɱɧɨɝɨ ɫɩɟɤɬɪɭ ɨɫɧɨɜɧɢɯ ɡɛɭɞɧɢɤɿɜ ɩɧɟɜɦɨɧɿʀ ɭ ɯɜɨɪɢɯ ɧɚ ɮɨɧɿ ɨɧɤɨɥɨɝɿɱɧɢɯ ɡɚɯɜɨɪɸɜɚɧɶ ɤɪɨɜɿ ɡɚɫɧɨɜɚɧɿ ɧɚ ɦɿɠɧɚɪɨɞɧɨɦɭ ɞɨɫɜɿɞɿ ɬɚ ɞɨɫɥɿɞɠɟɧɧɹɯ, ɹɤɿ ɩɪɨɜɟɞɟɧɿ ɜ ɡɚɪɭɛɿɠɧɢɯ ɤɪɚʀɧɚɯ [2, 4, 10, 12]. ɆȺɌȿɊȱȺɅɂ ɌȺ ɆȿɌɈȾɂ ȾɈɋɅȱȾɀȿɇɖ Ⱦɨɫɥɿɞɠɟɧɨ 149 ɯɜɨɪɢɯ ɧɚ ɩɧɟɜɦɨɧɿɸ ɧɚ ɮɨɧɿ ɨɧɤɨɥɨɝɿɱɧɢɯ ɡɚɯɜɨɪɸɜɚɧɶ ɤɪɨɜɿ, ɹɤɿ ɩɪɨɯɨɞɢɥɢ ɩɪɨɝɪɚɦɧɟ ɥɿɤɭɜɚɧɧɹ ɧɚ ɛɚɡɿ ɝɟɦɚɬɨɥɨɝɿɱɧɨɝɨ ɰɟɧɬɪɭ ɄɁ «Ⱦɧɿɩɪɨɩɟɬɪɨɜɫɶɤɚ ɦɿɫɶɤɚ ɛɚɝɚɬɨɩɪɨɮɿɥɶɧɚ ɤɥɿɧɿɱɧɚ ɥɿɤɚɪɧɹ ʋ 4 ȾɈɊ» ɩɪɨɬɹɝɨɦ 2010-2012 ɪɪ. Ɉɨɤɚɡɧɢɤɢ ɿɞɟɧɬɢɮɿɤɚɰɿʀ ɩɚɬɨɝɟɧɧɢɯ ɦɿɤɪɨɨɪɝɚɧɿɡɦɿɜ ɭ ɯɜɨɪɢɯ ɧɚ ɩɧɟɜɦɨɧɿɸ ɧɚ ɮɨɧɿ ɨɧɤɨɥɨɝɿɱɧɢɯ ɡɚɯɜɨɪɸɜɚɧɶ ɤɪɨɜɿ ɉɨɤɚɡɧɢɤɢ
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