Abstract
An 81-year-old female with Granulomatosis and polyangiitis on immunosuppression with methotrexate, steroids, and Rituximab but not on prophylaxis, developed a finding of Pneumocystis Jirovecii Pneumonia (PJP). She was treated with an alternative regimen, clindamycin and primaquine along with caspofungin and corticosteroids. Secondary prophylaxis with cotrimoxazole was initiated after completion of treatment. This case highlights the importance of early diagnosis, treatment difficulties, and the need for prophylaxis for HIV-negative patients on immunosuppressive treatment.
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