Abstract

Studies that report healthcare resource utilization (HcRU) among individuals diagnosed with Parkinson’s disease (PD) typically have short follow-up periods. Longitudinal information on HcRU is important given that PD evolves over time. This study's purpose was to investigate differences in HcRU for PD cases and controls over time. This retrospective study utilized administrative claims data from 2005 to 2015 for Medicare beneficiaries represented in the Medicare Chronic Condition Data Warehouse (CCW) 5% sample. We matched cases to controls based on age, race, gender and comorbidities. Differences in HcRU (hospitalization, skilled nursing facility (SNF), and non-PD drug utilization) were assessed during the follow-up period between PD cases and controls. For individuals with at least 1, 3, 5, 7 and 9 years of follow up, we calculated summary statistics based on proportions and counts of HcRU measures. The matched sample consisted of 15,172 cases & 15,172 controls. Among those with 1 year of follow up, a higher proportion of PD cases experienced an inpatient hospitalization (20% vs. 10%, p-value: < 0.01). A similar pattern existed among those with 9 years of follow-up (56% vs. 43%, p-value: < 0.01). We observed a similar pattern for SNF stays based on 1 year of follow-up (24% vs. 7%, p-value: < 0.01) and 9 years of follow-up (51% vs 24%, p-value: < 0.01). PD cases displayed increased HcRU with longer follow-up periods. For PD cases, the median number of SNF stays was 0 among those with 1 year of follow-up and 4 among those with 9 years of follow-up, compared to controls where the median number of SNF stays remained 0 across the periods. We characterized HcRU among a cohort of Medicare beneficiaries with and without Parkinson’s disease – related claims. Over time, PD cases consistently displayed higher HcRU as compared to controls.

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