PMU67 - Analysis of the Application Status of Quality of Life Scale Based on Traditional Chinese Medicine Theory in Chronic Hepatitis in China

Abstract

To understand the application status of quality of life (QOL) scales based on Traditional Chinese Medicine (TCM) theory in the field of chronic hepatitis in China. Researching “TCM", "Symptoms", "Quality of Life" and "Chronic Hepatitis" in Chinese periodical full-text database, CNKI, Wanfang, CQVIP and China Biomedical Literature Database. The search period is as of December 2017 (no starting date). Finally, there were 50 valid literature were selected. The main diseases of concern were chronic hepatitis B (30, 60%) and cirrhosis (12, 24%). There were 32 articles (64%) analyzed the development process and applicability of TCM QOL scale,11 (22%) were single evaluation of the literature on QOL of patients during studies conducted, and only 7 (14%) evaluated the impact of interventions on patient QOL. In the aspect of using the QOL scale, 35 articles (70%) used only the QOL scale based on TCM theory,7 articles (14%) also used SF-36, 6 articles (12%) additionally used the CLDQ scale, and only 2 articles (4%) used mental health measurement scale(SAS, SDS) simultaneously. These articles involved 27 QOL scales based on TCM theory, chronic hepatitis B(16, 59.26%), cirrhosis of liver (8, 29.63%) and chronic hepatitis C (3, 11.11%). TCM symptom scales (28 times, 56%) have higher application frequency, the next are The Chronic Hepatitis B Patients PRO scale (TCHB - PRO) (5 times, 10%), TCM liver disease PRO scale (4 times, 8%), Chronic Hepatitis B Chinese characteristics PRO scale (3 times, 6%), etc. The QOL scale developed on the basis of TCM theory of liver disease has gradually increased. But there are still many problems, such as not so standardized scale development program, mainly TCM syndromes, and less involved psychological and social support. The existing scales are mostly non-preference-based scales that could not be used for cost-utility analysis (CUA) of different interventions.