Evaluation on quality of life and analysis on its correlation with TCM syndromes in patients of chronic hepatitis B

Abstract

To evaluate the quality of life (QOL) in patients with chronic hepatitis B (CHB) and analyze its correlation with traditional Chinese medicine (TCM) syndrome types. With cross-sectional investigation adopted, the QOL of 335 CHB patients was studied by the World Health Organization Quality of Life BREF Questionnaire (WHOQOL-BREF) and the chronic liver disease questionnaire (CLDQ). The results was compared with that of 30 healthy persons. The QOL of the patients with chronic hepatitis B was lower than the healthy persons with signififi cant difference between them (P<0.01). Also it was different in patients of different TCM syndrome types (P<0.05 or P<0.01). The lowest QOL was shown in patients of the blood-stasis blocking vessel type and Gan ()-stagnation with Pi ()-defificiency type (P<0.01). The QOL of CHB patients is lower than of healthy persons and closely correlated with TCM syndrome types.