Abstract

Sepsis is a life-threatening medical emergency affecting 48.9 millions of people worldwide, accounting for 20% of global deaths in 2017. Early identification able to reduce Time To Antibiotics (TTA) may significantly reduce disease severity and mortality. However, serious delays still affect the management of septic patients and make urgent the need for a diagnostic test. Monocyte Distribution Width (MDW) is a new biomarker recently developed for the early detection of sepsis. This study aims to conduct a multidimensional and multi-stakeholder assessment of the MDW technology being at the stage-gate between clinical validation and translation into the Italian National Health System.

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