Abstract
Platelet-rich fibrin (PRF) is an autologous platelet concentrate with intimate assembly of cytokines, glycan chains, and structural glycoproteins, increased concentration of growth factors enmeshed within a slowly polymerized fibrin network, has the capability to accelerate soft tissue as well as hard-tissue healing. Platelets play a crucial role in the field of regenerative dentistry. A systematic search was conducted using Scopus, Medline PubMed, and Google Scholar up to and including March 2017, to identify relevant studies. All cross-reference lists of the selected studies were also screened. The inclusion criteria were articles those having detailed summary in English, published between 2006 and 2017. This review article concludes the literature in brief, role of PRF in healing, its clinical applications, and also the advantages and the disadvantages.
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