Abstract
Changes in platelet adhesiveness, using Wright's (1941) rotating-bulb method, and the development of deep-vein thrombosis detected by the 125I-labelled-fibrinogen-uptake method were studied in fifty patients undergoing surgical operations. Four of the twenty-four patients undergoing general surgical procedures, and thirteen of the twenty-six patients recovering from hip operations, developed postoperative deep-vein thrombosis. Platelet adhesiveness rose in thirty-six patients postoperatively, but no correlation was observed between either preoperative platelet adhesiveness or maximum postoperative platelet adhesiveness and the development of deep-vein thrombosis. There was no significant difference in changes in platelet adhesiveness between those patients who developed deep-vein thrombosis and those who did not. Changes in platelet adhesiveness do not seem to be of value in the prediction or diagnosis of postoperative venous thrombosis.
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