Abstract
The determinant for resistance to the antiseptics acriflavine, benzalkonium chloride and cetrimide and the intercalating dye, ethidium bromide has been physically mapped on pSK57, a penicillinase plasmid detected in strains of methicillin-resistant Staphylococcus aureus. Restriction endonuclease analysis and DNA-DNA hybridization indicate that this determinant is identical to that which encodes these resistances on the plasmid pSK1, which is the most frequently detected gentamicin resistance plasmid in methicillin-resistant S. aureus isolates from Australian hospitals.
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