Abstract

A DRENAL function in the presence of acute myocardial infarction has been studied by several investigators with conflicting results. It has been suggested that shock of cardiac origin may be related to an inadequate adrenal cortical reserve,Ie3 and clinical improvement has been noted following administration of cortisone.4 Conversely, adrenal cortical hyperfunction in myocardial infarction without shock has also been demonstrated both by increased plasma cortisol levels5 and urinary corticosteroid excretions.6 Whether or not cardiogenic shock is related to hypoor hyperadrenocortical function has not been documented adequately. This study is an attempt to evaluate adrenal cortical function in myocardial infarction with and without shock and to determine if there is any physiologic basis for the exogenous administration of cortisone.

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