Abstract
Plasma cell gingivitis is a rare benign condition characterized by the inflammatory infiltration of plasma cells, secondary to a hypersensitivity reaction to allergens found in oral hygiene products. This study aimed to present the case of a 48-year-old female, who was admitted to our clinic complaining of an intense gingival discomfort for the past six months, with the onset of symptoms occurring after using a new toothpaste. Clinical examination revealed generalized gingival erythema and edema. An incisional biopsy was performed, which, through direct immunofluorescence, revealed connective tissue densely permeated by interstitial lymphoplasmohistiocytic inflammatory cells, a condition that must be distinguished from other autoimmune diseases. The diagnosis of plasma cell gingivitis was concluded with a detailed history, differential diagnoses, and histopathology. The elimination of the etiologic factor, namely the toothpaste, and the use of topical corticosteroids improved both the lesions and the symptoms. Plasma cell gingivitis is a rare benign condition characterized by the inflammatory infiltration of plasma cells, secondary to a hypersensitivity reaction to allergens found in oral hygiene products. This study aimed to present the case of a 48-year-old female, who was admitted to our clinic complaining of an intense gingival discomfort for the past six months, with the onset of symptoms occurring after using a new toothpaste. Clinical examination revealed generalized gingival erythema and edema. An incisional biopsy was performed, which, through direct immunofluorescence, revealed connective tissue densely permeated by interstitial lymphoplasmohistiocytic inflammatory cells, a condition that must be distinguished from other autoimmune diseases. The diagnosis of plasma cell gingivitis was concluded with a detailed history, differential diagnoses, and histopathology. The elimination of the etiologic factor, namely the toothpaste, and the use of topical corticosteroids improved both the lesions and the symptoms.
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