Abstract
We evaluated the effects of pancuronium and opiates on plasma β-endorphin concentrations in 25 infants supported by mechanical ventilation. Infants receiving opiate were randomly assigned to receive either fentanyl or morphine. There was no change in β-endorphin concentrations after administration of pancuronium, whereas both fentanyl and morphine reduced β-endorphin concentrations by approximately 60%. (J P EDIATR 1994;125:113-6)
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