Abstract
SIRC cells, which have been shown to support plaque formation of rubella virus, were found to consist of a number of cell clones with different degrees of virus susceptibility. Clones isolated from the original SIRC cell population were classified by their ability to form plaques into 3 groups; namely clones producing 1) clear plaques, 2) pin-hole plaques, and 3) no plaques. It was pointed out that in some clones, these characteristics were relatively unstable during subcultivations. The most favorable concentration of sodium bicarbonate for plaque formation of rubella virus was 0.2–0.4%. The addition of DEAE-dextran prior to viral inoculation enhanced the efficiency of plaquing.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
