Abstract
Placental-origin diseases, stemming from placental dysfunction, impact maternal and fetal health. This article reviews scientific and clinical advancements, emphasizing molecular insights and innovative diagnostics and treatments. It notes that placental issues are associated with signaling pathway dysregulation and epigenetic responses to environmental influences. Clinical tools like Doppler ultrasound and noninvasive DNA testing improve early disease detection. Personalized medicine, considering genetic and lifestyle elements, presents new management strategies. Challenges due to disease diversity and individual differences remain, with a call for future research to focus on biomarker identification, environmental-genetic interactions, and interdisciplinary efforts to advance diagnostics and therapeutics.
Published Version
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