Abstract
AbstractCathinone derivatives (CD) are psychostimulant (and/or hallucinogenic for some of them) drugs with the phenylethylamine structure of amphetamine compounds, and belong to new psychoactive substances (NPS). This manuscript aims to introduce DC and to draw toxicological analysis situation in patterns of identification and management of abuse and hazards associated to CD. Currently in France, CD-related health hazards mainly (but not exclusively) take place in the chemsex area (refer to the use of psychoactive drugs in sexual parties, and is particularly prevalent among the community of men who have sex with men) where the leading CD seems likely to be 3-methylmethcathinone (3-MMC). Toxicological analysis take place in early warning systems for CD, medical or forensic case of acute intoxication related to CD use, follow-up addiction care and harm reduction policy. Analysis of biological samples (blood, urine and hair) are performed using liquid chromatography with high resolution mass spectrometry detection and gas chromatography with mass spectrometry detection methods, together with nuclear magnetic resonance methods for powders analysis.
Published Version
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