Abstract
Steroids have revolutionized modern-day medicine, aiding in the treatment of a broad range of diseases, including arthritis, lupus, and multiple sclerosis. The pioneering research on steroids at the Upjohn Company was honored with a National Historic Chemical Landmark during a May 17 ceremony at the Kalamazoo Valley Museum in Kalamazoo, Michigan, where Upjohn was founded in 1886. “Many of these modern drug therapies would not be available today without the pioneering research and development that occurred at Upjohn over an incredible 60-year period starting in 1930,” says American Chemical Society immediate past president Peter Dorhout. “The medicinal chemistry innovations, microbial and chemical transformation discoveries, and manufacturing processes developed by Upjohn for its steroid medicine program transformed not only the pharmaceutical industry but also the entire field of synthetic organic chemistry.” In 1935, Upjohn became the first company to market an adrenocortical steroid product, and by the ...
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