Abstract
Abstract This reaction is the synthesis of vicinal diols from carbonyl compounds via reductive coupling. Because vicinal diol (or 1,2‐diol) is generally known as pinacol, the reductive coupling of carbonyl compounds to give vicinal diols is known simply as the pinacol coupling or pinacol coupling reaction. It has been reported that the molecules, which can be reduced to radicals or radical anions, undergo similar radical coupling reaction. The large number of low‐valent metals and their salts or complexes have been found to promote this reaction. It has been observed that the multicomponent system of tricarbonyl(benzaldehyde)chromium/SmI 2 gives high threo ‐selectivity. It has also been pointed out that the homogeneous reaction conditions often give higher diastereoselectivies than the heterogeneous ones. This reaction has general application in the preparation of vicinal diols.
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