Abstract

BackgroundCase investigation and reactive case detection (RACD) activities are widely-used in low transmission settings to determine the suspected origin of infection and identify and treat malaria infections nearby to the index patient household. Case investigation and RACD activities are time and resource intensive, include methodologies that vary across eliminating settings, and have no standardized metrics or tools available to monitor and evaluate them.MethodsIn response to this gap, a simple programme tool was developed for monitoring and evaluating (M&E) RACD activities and piloted by national malaria programmes. During the development phase, four modules of the RACD M&E tool were created to assess and evaluate key case investigation and RACD activities and costs. A pilot phase was then carried out by programme implementers between 2013 and 2015, during which malaria surveillance teams in three different settings (China, Indonesia, Thailand) piloted the tool over a period of 3 months each. This study describes summary results of the pilots and feasibility and impact of the tool on programmes.ResultsAll three study areas implemented the RACD M&E tool modules, and pilot users reported the tool and evaluation process were helpful to identify gaps in RACD programme activities. In the 45 health facilities evaluated, 71.8% (97/135; min 35.3–max 100.0%) of the proper notification and reporting forms and 20.0% (27/135; min 0.0–max 100.0%) of standard operating procedures (SOPs) were available to support malaria elimination activities. The tool highlighted gaps in reporting key data indicators on the completeness for malaria case reporting (98.8%; min 93.3–max 100.0%), case investigations (65.6%; min 61.8–max 78.4%) and RACD activities (70.0%; min 64.7–max 100.0%). Evaluation of the SOPs showed that knowledge and practices of malaria personnel varied within and between study areas. Average monthly costs for conducting case investigation and RACD activities showed variation between study areas (min USD $844.80–max USD $2038.00) for the malaria personnel, commodities, services and other costs required to carry out the activities.ConclusionThe RACD M&E tool was implemented in the three pilot areas, identifying key gaps that led to impacts on programme decision making. Study findings support the need for routine M&E of malaria case reporting, case investigation and RACD activities. Scale-up of the RACD M&E tool in malaria-eliminating settings will contribute to improved programme performance to the high level that is required to reach elimination.

Highlights

  • Case investigation and reactive case detection (RACD) activities are widely-used in low transmission settings to determine the suspected origin of infection and identify and treat malaria infections nearby to the index patient household

  • Eight per cent (3/34) of health facilities examined in Aceh had standard operating procedures (SOP) or instructions on the reporting processes for case notification, investigation or RACD; Ranong, Thailand had zero (0/5) and Jiangsu, China reported 100% (6/6)

  • Most study areas had organizational diagrams of the malaria personnel involved in case investigation and RACD activities [88.2% (30/34) in Aceh; 100.0% (6/6) in Jiangsu; 100.0% (5/5) in Ranong]

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Summary

Introduction

Case investigation and reactive case detection (RACD) activities are widely-used in low transmission settings to determine the suspected origin of infection and identify and treat malaria infections nearby to the index patient household. ACD strategies are designed to identify and treat malaria infections as early as possible, before they are symptomatic and reduce the reservoir of infection responsible for continued malaria transmission [2, 3]. One commonly used ACD approach is reactive case detection (RACD). This surveillance and response strategy involves case investigation, whereby passively detected malaria cases (index case) are traced to their residence to determine the suspected origin of infection (local, introduced or imported infection), and ascertain if onward transmission of malaria is possible. RACD is conducted around an index case because evidence suggests that additional malaria infections cluster in close proximity to the index household [4,5,6]

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