Abstract
Synedrella nodiflora is a useful medicinal plant that has been evaluated for its application in treatment of several ailments in sub-Saharan Africa and Bangladesh since time immemorial. In the present study, the methanol extract of the plant was investigated in-vitro for the presence of some essential phytochemicals, its antioxidant capacities, activity inhibition of skin degenerating enzymes of elastase and tyrosinase as well as its anti-lipid peroxidation activity. Determination of the total antioxidant capacities of the extract was achieved through evaluation of oxygen radical absorbance capacity (ORAC), ferric ion reducing antioxidant potential (FRAP) and iron-II induced inhibition of lipid peroxidation (LPO) assays.
Highlights
Many plants in nature have been assessed for their medicinal values
The background knowledge of the chemical constituents of a plant is highly desirable for the discovery of therapeutic agents and because such information may be of value in disclosing new sources of economic materials like tannins, polyphenols, gum, oils, and other precursors for the synthesis of complex chemical substances [1]
The phytochemical constituents of medicinal plants have been reported to be directly associated with their biological activities [10, 25, 38]
Summary
Many plants in nature have been assessed for their medicinal values. The background knowledge of the chemical constituents of a plant is highly desirable for the discovery of therapeutic agents and because such information may be of value in disclosing new sources of economic materials like tannins, polyphenols, gum, oils, and other precursors for the synthesis of complex chemical substances [1]. Phytochemical screening enables tracing of the medicinal value of plants constituent and some biochemi cal substances that generate a definite physiological action on the human body [2,3]. Some important of the bioactive compounds in plants are the alkaloids, flavanol, flavonoids, tannins, alkaloids saponins, glycosides, cardenolides, proanthocyanidins and polyphenolic compounds [4,5,6,7].
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