Abstract
This paper is intended to review advances in the botanical, phytochemical, traditional uses and pharmacological studies of the genus Trachelospermum. Until now, 138 chemical constituents have been isolated and characterized from these plants, particularly from T. asiaticum and T. jasminoides. Among these compounds, lignans, triterpenoids, and flavonoids are the major bioactive constituents. Studies have shown that plants from the genus Trachelospermum exhibit an extensive range of pharmacological properties both in vivo and in vitro, including anti-inflammatory, analgesic, antitumor, antiviral and antibacterial activities. In Traditional Chinese Medicine (TCM) culture, drugs that include T. jasminoides stems have been used to cure rheumatism, gonarthritis, backache and pharyngitis, although there are few reports concerning the clinical use and toxicity of these plants. Further attention should be paid to gathering information about their toxicology data, quality-control measures, and the clinical value of the active compounds from genus Trachelospermum.
Highlights
The genus Trachelospermum L., a member of the dobane family Apocynaceae and first described as a genus in 1851, is widely distributed in Asia and is native to the subtropical regions .The general name of the genus is Caulis Trachelospermi
This review presents a comprehensive summary of the botany, phytochemistry, traditional uses and pharmacology of the genus Trachelospermum
Research on bioactive components are concentrated in lignans and flavonoids, which may contribute either directly or indirectly to the biological effects of the Trachelospermum genus
Summary
The genus Trachelospermum L., a member of the dobane family Apocynaceae and first described as a genus in 1851, is widely distributed in Asia and is native to the subtropical regions. The dried leaves and stems of the genus plants can be used as medicine. The stems of Trachelospermum plants have been used as local and traditional medicine in China, Japan and Korea, etc. Plants of the genus Trachelospermum are enriched in multiple structurally. Plants of the genus Trachelospermum are enriched in multiple structurally diverse and biologically important lignans [1] andastheir glycosides, as well as diverse and biologically important lignans [1] and their glycosides, well as triterpenoids [2] and triterpenoids and flavonoids [3]. Believe this paper willfull be autilization guide for the from this genusisolated are alsofrom discussed Weare believe this paperWe will be a guide for the of full utilization of Trachelospermum plants for new drug development and pharmaceutical applications
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