Abstract
Objective: This study was designed to evaluate the phytochemicals present in the flower and leaf extracts of Clerodendrum paniculatum L., collected from Nelji village of Kodagu district .
 Methods: The healthy leaves and flowers of C. paniculatum were collected and the plant extracts were prepared using ethanol, hexane and distilled water separately. Phytochemical analysis was conducted using standard procedurs for the flower and leaf extracts of C. paniculatum. The antioxidant activity in leaf and flower extracts was determined by three assays, estimation of total phenolic content, reducing power assay and radical scavenging activity (DPPH) using standard procedures.
 Results: Phytochemical screening conducted for the flower and leaf extracts of C. paniculatum showed the presence of three phytochemicals, namely saponins, alkaloids and terpenoids. Terpenoids were commonly present in all the extracts of flower and leaf that is in both polar (aqueous and ethanol) solvent and in non-polar (hexane) solvents. The extracts tested for the antioxidant activity showed the presence of total phenolics in ethanol, aqueous and hexane extracts. The aqueous extract showed high redox potential followed by ethanol and hexane extracts. The aqueous leaf extract showed high radical scavenging activity when compared to the flower extracts of C. paniculatum.
 Conclusion: The present study showes C. paniculatum to be an important medicinal plant, since the flower and leaves showed good antioxidant activity. Thus it may used in the treatment of diseases and may also used in the preparation of natural or herbal drugs due to the presence of antioxidants.
Highlights
Medicinal plants are the richest bioresource of drugs of traditional systems of medicine, modern medicines, nutraceuticals, food supplements, folk medicines, pharmaceutical intermediates, and chemical entities for synthetic drugs [1]
The hexane extract of flower showed the presence of terpenoids (Fig. 2)
Reducing power assay was based on the principle that is substances which have reduction potential react with potassium ferricyanide (Fe 3+) to form potassium ferrocyanide (Fe2+), it reacts with ferric chloride to form a ferric ferrous complex which has a maximum absorption at 700 nm [17]
Summary
Medicinal plants are the richest bioresource of drugs of traditional systems of medicine, modern medicines, nutraceuticals, food supplements, folk medicines, pharmaceutical intermediates, and chemical entities for synthetic drugs [1]. From the traditional medicinal plants reported in the classic texts such as Ayurveda and Charaka Samhita, have contributed toward this boom in drug discovery. Some of the classical examples of drug discovery are morphine, quinine, and digoxin [2]. Phytochemicals are naturally occurring in the medicinal plants that contain defense mechanism and protect from various diseases [4]. Antioxidants are the substances that significantly delay or inhibit oxidative damage to a target molecule. Antioxidants prevent cell and tissue damage they act as scavengers [5]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
