Abstract

Croton macrostachyus which is called ‘rush foil’ or ‘broadleaved croton is a multipurpose, medium sized, drought-deciduous pioneer tree. It is a tall tree found in tropical regions of Africa. The genus Croton belongs to the family Euphorbiaceae, which commonly known as the ‘spurge’ family, and it is known as ‘Bisana’ (in Amharic). Traditionally, C. macrostachyus used for treatment of malaria, rabies, gonorrhea, wound, diarrhea, hepatitis, jaundice, scabies, toothache, abdominal pain, cancer, typhoid, pneumonia and gastrointestinal disorders and as ethno-veterinary medicine. The air dried and powdered plant material (400g) was first soaked with 500mL n-hexane for 48hours and yielded 2g of n-hexane extract. Marc was soaked with 500mL of chloroform for 36hours and afforded 3.5g of chloroform extract. Finally, Marc was soaked with 500mL of methanol and yielded 18g of methanol extract. The chloroform extract of the stem bark of C. macrostachyus afforded a compound coded as EO . Its Structural determination was accomplished by means of spectroscopic techniques, namely IR, 1 H NMR, 13 C NMR and DEPT-135. The compound, EO was isolated and characterized from the stem bark of C. macrostachyus . Generally, more advanced chromatographic techniques are required to isolate more compounds from stem bark of C. macrostachyus . Also MS and 2D NMR spectroscopic techniques are needed to fully characterize the isolated compound. Keywords: C. macrostachyus; ethno-veterinary; characterization; chromatographic techniques; spectroscopic techniques. DOI: 10.7176/CPER/63-01 Publication date: October 31 st 2020

Highlights

  • Plants are invaluable and fundamental to almost all life on earth

  • C. macrostachyus used for treatment of malaria, rabies, gonorrhea, wound, diarrhea, hepatitis, jaundice, scabies, toothache, abdominal pain, cancer, typhoid, pneumonia and gastrointestinal disorders and as ethno-veterinary medicine

  • C. macrostachyus used for treatment of malaria, rabies, gonorrhea, wound, diarrhea, hepatitis, jaundice, scabies, toothache, abdominal pain, cancer, typhoid, pneumonia and gastrointestinal disorders and as ethnoveterinary medicine.[22,23,24]

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Summary

Introduction

Plants are invaluable and fundamental to almost all life on earth They provide wide range of uses to human beings such as medicine, food, shelter, clothing, fuel wood for cooking, timber for construction, utensils, as well as fodder for cattle. They recycle essential nutrients of ecosystems, establishing soils and maintaining soil fertility in addition to protecting areas of water catchments. They keep ecological and climatic balance, facilitate, and control rainfall through the process of evaporative transpiration.[1, 2] Croton macrostachyus Hochst. In Ethiopia, for example, C. macrostachyus is a major tree intercropped in agroecosystems in order to increase soil productivity in midaltitude and semiarid areas.[9]

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