Abstract
This paper reports on the phytochemical composition as well as antiradical and anticholinesterase potential of volatile oils isolated from Centaurea alba and Centaurea jacea, from Croatia. The volatile components, obtained by hydrodistillation, were determined by GC and GC-MS analyses. A total of 18 compounds were identified in C. alba volatile oil with hexadecanoic acid, germacrene D and tetradecanoic acid as main compounds. A total of 29 compounds were identified in C. jacea volatile oil, with epi-bicyclosesquiphellandrene, aromadendrene and hexadecanoic acid as a major compounds. The tested volatile oils showed low DPPH inhibition potential as well as low to moderate antiAChE potential and low antiBuChE potential.
Highlights
T HE genus Centaurea L. is one of the richest genera in the Asteraceae family
This is the first report about chemical composition of Centaurea alba L. and the second report about chemical composition of Centaurea jacea L. volatile oil, but the first one for the plant from Croatia
This is the first report about chemical composition of Centaurea alba and the second report about chemical composition of Centaurea jacea volatile oil, but the first one for the plant from Croatia
Summary
T HE genus Centaurea L. is one of the richest genera in the Asteraceae family. According to today's concept, genus contains about 250 species which have the main spreading area in the Mediterranean region.[1,2]The genus Centaurea had been extensively used in folk medicine for hundreds of years, especially in eastern Mediterranean ethnopharmacology.[3–5] It is confirmed that noumerous Centaurea species have biological potential, as antimicrobial, antifungal, antiviral, antiHelicobacter pylori, antiulcerogenic, antioxidant, antiinflammatory and cytotoxic.[3,6–13]Plants are good source of volatile components that are important in biological and ecological terms. As a part of our research on the phytochemical composition and biological potential of Croatian Centaurea sp.[16–18] we report here the results of phytochemical composition as well as antiradical and anticholinesterase potential of Centaurea alba L. and Centaurea jacea L. volatile oils from Croatia.
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