Abstract
Daucosterol (1) was isolated from the n-hexane soluble fraction of a methanol extract of the stems of Sida rhombifolia Linn. (Syn. S. rhomboidea Linn.). The n-hexane, carbon tetrachloride and dichloromethane soluble fractions of this methanol extract were subjected to antimicrobial and antioxidant screening as well as brine shrimp lethality bioassay. The dichloromethane and carbon tetrachloride soluble fractions showed moderate inhibitory activity to microbial growth while the n-hexane fraction showed highest cytotixicity having LC50 0.84 μg/ml. The dichloromethane soluble fraction also revealed potent antioxidant activity with IC50 20 μg/ ml.
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