Abstract
Routine measurements of arterial Po2, Pco2, oxygen saturation of hemoglobin, P50, hemoglobin content allow a more accurate approach in the treatment of hypoxia in the neonate. Based upon these routinely available determinations and upon the clinical evaluation of the peripheral circulation, four types of hypoxia can be distinguished: (1) Hypoxia with hypoxemia due to a decrease in arterial Po2. (2) Hypoxia with hypoxemia due to a decrease in blood oxygen content without decrease in arterial Po2. (3) Hypoxia with normoxemia due to a decrease in peripheral blood flow. (4) Hypoxia with normoxemia due to an increase in the hemoglobin-oxygen affinity. Hyaline membrane disease represents a possible combination of these four different mechanisms.
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