Physiological parameters in broiler lines divergently selected for the incidence of ascites

Abstract

Ascites syndrome (AS) is manifested in flocks of contemporary broilers that are allowed to fully manifest their genetic potential for rapid growth. After successful selection, a pair of divergent lines was established, AS-susceptible (AS-S) and AS-resistant (AS-R). These lines facilitate comparisons between genetically resistant and susceptible healthy young broilers when reared under standard brooding conditions (SBC). The aim of the present study was to look for predictive indicators for AS susceptibility by comparing relevant physiological parameters in the AS-S and AS-R lines under SBC and after exposure to extreme ascites-inducing conditions (AIC). In this design, a trait differing significantly between the 2 lines under SBC is expected to be a reliable indicator for selection against AS susceptibility in breeding stocks when reared under noninducing conditions. Males from the AS-S and AS-R lines were reared together under SBC to 19 d of age, then under the AIC protocol. Cumulative incidence of AS mortality was 93.2% in the AS-S line and only 9% in the AS-R line, confirming the genetic divergence between the lines. Exposure to AIC enhanced the imbalance between oxygen demands and supply in the AS-S birds and induced differences in blood parameter level between the 2 lines. The AS-S birds exhibited elevated hematocrit and red blood cell counts and a decline in oxygen saturation in the arterial blood. No difference in hemoglobin concentration was found, but calculation of hemoglobin content per 1,000 red blood cells revealed a significant reduction in hemoglobin content in the AS-S birds. Under SBC, there were no significant differences between the lines for hematocrit, red blood cell count, hemoglobin concentration, hemoglobin count per 1,000 red cells, and blood oxygen saturation. However, heart rate during the first week of life was significantly higher in the AS-S birds than in the AS-R birds on d 1 and 7, suggesting that high heart rate may potentially serve as an early criterion for selection against AS susceptibility.