Abstract
To investigate the physiological characteristics of the human pylorus, simultaneous measurements of intraluminal pressure and skin to mucosa potential difference were determined in 28 normal subjects. The radiographic junction of the stomach and duodenum was marked by a potential difference change of −33.7 ± 2.8 mv (mean ± SE) and a high pressure zone with an amplitude of 5.3 ± 0.5 mm Hg and a length of 1.5 ± 0.1 cm. A diminution in pressure at the pylorus occurred with antral peristalsis. During the infusion of 0.1 N HCl into the duodenum, pyloric pressure increased to 17.2 ± 1.4 mm Hg ( P P
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