Abstract
Boron Neutron Capture Therapy (BNCT) research in the United States has focused on the use of epithermal (0.5 eV to 10 key) neutron beams for treatment of certain highly-malignant primary brain tumors and possibly for treatment of metastatic malignant melanoma. Various types of epithermal neutron sources for BNCT have been proposed over the years. Reactor-based sources, accelerator-based sources, and radioactive neutron sources have all been extensively examined. The first practical, large-scale, epithermal neutron beam for BNCT was installed at the Brookhaven Medical Research Reactor (BMRR)1. This beam was designed and constructed in a cooperative effort between Brookhaven National Laboratory (BNL) and the Idaho National Engineering Laboratory (INEL). It has been used extensively for BNCT research activities conducted by INEL, BNL, and others.
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