Physicochemical Properties and Bioactive Potential of a New Epoxy Resin-based Root Canal Sealer.

Mario Tanomaru-Filho,Juliane Maria Guerreiro-Tanomaru,Raqueli Viapiana,Mariana Mena Barreto Pivoto-João,Fernanda Ferrari Esteves Torres,Maiby Cristine Prado

doi:10.1590/0103-6440201802861

Mario Tanomaru-Filho, Juliane Maria Guerreiro-Tanomaru + Show 4 more

Open Access

https://doi.org/10.1590/0103-6440201802861

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Abstract

The aim of this study was to evaluate physicochemical properties and bioactive potential of Sealer Plus, in comparison with MTA Fillapex, Sealapex and AH Plus. Setting time, flow, and radiopacity were evaluated based on ISO 6876 Standard. Flow was also assessed in area (mm²). The solubility and volumetric change of the sealers were evaluated after 7 and 30 days of immersion in distilled water. Solubility was evaluated by the difference in mass of materials before and after immersion. Volumetric change was evaluated by using microcomputed tomography (micro-CT). The bioactive potential was observed by Scanning Electron Microscopy (SEM) after immersion in PBS. Data were compared using ANOVA and Tukey tests (α=0.05). Sealer Plus presented the shortest setting time (196 min.) and Sealapex the longest (912 min.) (p<0.05). AH Plus showed the highest radiopacity (9.5 mm Al) and MTA Fillapex the lowest (2.7 mm Al) (p<0.05). All the sealers presented flow in accordance with ISO 6876/2012 (>17 mm). Sealer Plus showed low solubility and volumetric change (<1%), and MTA Fillapex showed the highest solubility (>25%), and volumetric change (>4%) after all time intervals (p<0.05). MTA Fillapex was the only sealer that showed bioactive potential. In conclusion, Sealer Plus presented proper physicochemical properties. However, this sealer did not present a bioactive potential.

Highlights

The development of sealers with proper physicochemical and biological properties is important for successful endodontic treatment (1)
Root canal filling materials are investigated by using standardized tests to evaluate setting time, flow, solubility, and radiopacity (3)
The addition of calcium hydroxide in Sealer Plus may justify its shorter setting time, which could be related to the hydration of the sealer (18)

Summary

Introduction

The development of sealers with proper physicochemical and biological properties is important for successful endodontic treatment (1). Root canal sealers should be bioactive stimulating repair of the periapical tissues (2). Root canal filling materials are investigated by using standardized tests to evaluate setting time, flow, solubility, and radiopacity (3). The setting time should be long enough to allow the root canal filling (3). A proper flow allows sealer to penetrate into the irregularities of root canal system (4). A low solubility prevents change in structure or integrity of the sealer (5). The radiopacity allows radiographic evaluation of root canal filling (4). Microcomputed tomography (micro-CT) have been proposed to evaluate physical properties of endodontic materials (6-8). Micro-CT is a non-destructive tool, which presents the ability to evaluate materials three-dimensionally over time (7,8)

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