Abstract
Gabapentin usually has a good safety profile with adequate tolerance. The incidence of adverse reactions in skin, hair and mucosa due to gabapentin is low. Here, we present a case of lichenoid photosensitive eruption due to application of gabapentin in exposed areas. A lichenoid eruption with skin lesions that are widespread distributed requires a drug history as well as stopping the consumption of the drug in question. Patch test and/or phototest confirm the diagnosis.
Highlights
Gabapentin is useful to treat epilepsy, neuropathic pain and essential tremor
Gabapentin is approved by the Food and Drug Administration for epilepsy and postherpetic neuralgia
The mechanism of action of gabapentin remains unknown, but it is believed that it causes an inhibition of alpha 2 delta voltage dependent calcium channel subunit leading to reduced neurotransmitter release and decreased postsynaptic excitability
Summary
Gabapentin is useful to treat epilepsy, neuropathic pain and essential tremor. It has a good safety profile with adequate tolerance and low incidence of adverse reactions. Several skin eruptions due to gabapentin have been reported. The patient was treated with oral gabapentin 300 mg/day for trigeminal neuralgia two weeks before this skin reaction. The patient had not been previously treated with gabapentin and was subject to no other medical treatment at the time.
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